| 名称 | TP53 p.R249S Reference Standard 标准品 |
| 型号 | CBP10156 |
| 报价 |  |
| 特点 | TP53 p.R249S Reference Standard |
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CBP10156 | |
| Format | Genomic DNA |
| Description | TP53 R249S is a hotspot mutation within the DNA-binding domain of the Tp53 protein (PMID: 22713868). R249S results in decreased DNA binding and transactivation activity of Tp53, and confers context-dependent transforming ability in cell culture (PMID: 20212049, PMID: 20538734). |
| Technical Data | |
| DNA Change: | c.747G>C |
| AA Change | p.R249S |
| Mutation type | Substitution - Missense |
| Zygosity | Homozygous |
| Allelic Frequency | 100% |
| Transcript | ENST00000269305 |
| Cosmic ID | COSM10785 |
| Chr position(GRCh37) | chr17:7577534 |
| Buffer: | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |
|
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
